Canvax Neuropeptide Y Receptor Y4 G0590-B

Neuropeptide Y Receptor Y4, ExpressMAX™ Human GPCR ORF Clones

NPY is a 36-amino acid peptide present in the brain and Peripheral Nervous System in nerve endings, from which it is coreleased with norepinephrine (NE) during stress. Several observations suggest that NPY is an important neurotransmitter involved in the central and peripheral control of blood pressure. NPY stimulates at least six types of GPCRs, called Y1, Y2, Y3, Y4, Y5 and Y6. No functions in the cardiovascular system have been associated with the Y4 and Y5 receptors.

Main Features:

Native structure. Wide range: A large collection of ExpressMAX™ GPCR ORF Clones availables. Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry. Wide spectrum: of strong constitutive promoters. Complete solution: it contains all necessary elements for maximum receptor expression. Ready-to-use solution: avoids cloning steps, DNA ready to transfect. Easy protocol and detection: the whole procedure is simple, with minimal handling. Neomycin resistance. Ampicillin bacterial selection.

Includes: Includes for 15 µg: ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B) - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) Mammalian Transfection Kits (Cat. No. -PLUS): - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) - 0.2 mL CANFAST™ Transfection Reagent (15 µg = 15 assays)

Applications: Functional assays, as protein immobilization, cellular localization and other functional assays. High-throughput and large scale protein production and purification. Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).