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Why You Should Choose Hard-Shell PCR Microplates

Microplates, how did it all start?

Researchers today owe thanks to Dr Gyula Takátsky, the Hungarian scientist and inventor who invented the first microplate in 1951. An influenza pandemic had generated a shortage of test tubes and pipettes, prompting this development. Dr. Takátsky also invented platinum spiral loops that could be calibrated to replace pipettes, allowing him to continue his research without interruption. The original microplate by Takátsky was constructed of Lucite (Polymethyl Methacrylate or PMMA). Microplates grabbed on and boosted research a few years after he published articles telling the world of what he had done.

Microplates Today

Microplates are currently utilized for quantitative and qualitative high-throughput screening and research all around the world. They are made in a variety of sizes, shapes, materials, colours, and surface coatings to suit any application. The costs range from a few pounds to hundreds of pounds and can consume a significant percentage of the budget. Experience has shown us that it is financially prudent not to compromise on product quality. The quality and kind of materials used in the construction have an influence on performance by defining robustness and influencing absorption or interaction with chemicals within the wells, therefore impacting outcomes. Choosing the appropriate microplate for your experiment might save you time, money, and effort while also improving the quality of your findings. Understanding the materials, characteristics, and performance of your chosen plate is thus a distinct advantage.

When to use a Hard-shell PCR Microplate

Microplate warping, shrinkage, or distortion has a negative impact on robotic handling, seal integrity, and, ultimately, your outcomes. The skirt and deck of hard-shell PCR plates are constructed of a stiff two-component thermostable polypropylene. This material is unaffected by changes in temperature, pressure, or humidity, and due to its inert nature, it is nonreactive with the substances with which it comes into contact. Hard-shell microplates are thus an excellent choice for experiments involving heat cycling because they are unaffected by sterilizing processes.

Top 3 Reasons why choose Hard-shell PCR Microplates

1. Rigid two-component hard-shell microplates are not meant to distort during temperature changes, such as during a PCR cycle or sterilization. This enables the plate to endure the rigors of a PCR cycle, minimizing variability between wells and allowing for more accurate results.
2. The use of thermostable polymers ensures that plate size and form remain stable and predictable under precision robotic manipulation. This indicates that the plate performance is more consistent across data sampling.
3. To reduce expenses and increase return on investment. It makes economic sense to invest in consistent, dependable equipment to prevent unnecessary waste. High-quality products improve performance and, as a result, save expenses.

Let’s Summarise

Hard-shell microplates are the ideal choice for temperature-changing operations. Manufacturing is a complicated process that requires specialized expertise and equipment, as well as the careful selection of high-quality materials. The consistency, precision, and dependability of excellent quality hard-shell microplates are provided by their stability. Always get microplates from reputable manufacturers who use appropriate medical grade or molecular biology grade materials for maximum performance.

An excellent example is the iST Exo-Frame, which has a grey polycarbonate frame to prevent warping during PCR testing. Our hard-shell microplate also has transparent bottomed wells for improved imaging. For adaptability and performance, scientists across a wide range of study disciplines have selected this combination.

Lab Unlimited has a extensive range of iST Hard-shell PCR Microplates for all your needs.